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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f418e84cd65453c211afb87c11d5f8c0692923e0fb18e287839d0dcaf181870d' 
  AND token = 'LnCYDAxZhyxtXprTZtSQAt5dECRhenyVdyQITFf2nBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}