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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c7cea620ab9038310ddb1ece7bd8462afa8a0b3f3b94b9ced338c87ec5cdd3' 
  AND token = 'jS4SfschXCf18HrAnhkoTSIRG6dl9wYOS8wZIn/xSjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}