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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aa74477b2be04e7027194c5d249e4c545b5de3e7df62b68292ad9dd7b757169' 
  AND token = 'wpvkWU2MLiJK7kJOGeMB0xcvq1Pxnj1USyRWvVWtjEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}