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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '385bd7275c15f834cfb1818d49561b8cd06b4ab247337be60ea2d21cd19ec5cc' 
  AND token = 'F3cdPLVUa0EXG3LFMrzcMhZI73b4c1ovyGIbNt0/jA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}