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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5fdcd6ca1628b9480f764406e146b13c3eed7b00204ace6d61f01aec741e367' 
  AND token = 'XCSH1O95QL28Plxaa0GICOs5G+nmx+aUh3Uc/RudJCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}