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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0724b5870c94367da13868b3e977ad96a38f25ab0d2988a30d59d24c7dea0c8' 
  AND token = 'lVW53qgK3K83CgIxTYkGfman+jWmQDajGWYVY/QQR2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}