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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a8d927468fac211719651224ade3a723bb4cf17cd5a1641e915e5fcbfdf9cd5' 
  AND token = 'Gz28QvJxFu8eXrEa4CQO01zIrCEvG3NR7yk/24DnZyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}