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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f16b6077d61a33f0283796a531a3c51b173310eef7cfaaf473e9470ebdab716' 
  AND token = 'yH/wTwPjAbmxkzyQLtCzjTKbHYo37VejHv9FZF0zoQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}