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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67f6271c945c70b89e0c8ef9828f81711aba98d3a52c45a9aa624b10dabcd851' 
  AND token = 'nSb5IGhA3GZwyMV8g4xU6WjVrcYLqSS2aXOlEC8DMgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}