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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4379d4d81bf4ad6bb28c056137a260376c001aef4516f78e49559301c018e887' 
  AND token = '6gpcmhkO25s2i9Db0oJrsM8YYAaq3jCb4RbMW/uAMSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}