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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d2db72f44d8c5d61dd3f9d293dd587912af2eb88c89424fd7f8d219c4d4f46' 
  AND token = 'FG4I6G1xZfkmb40eQlNzXvBDxB7Mww+VGVGzAaIK7jE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}