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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b75c9ea836b4bf110c6650f2038188b377dcf2fb13ab2d586c2896a2b2a0113a' 
  AND token = 'FkS8Oz6UUEdEpZCnn/LM7xm9WoGrfz14PT3MQRUuhEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}