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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f706244cc872c3cd2b54ad65f79e1243fe1b1f2adf7ba2b54ea261147d02962' 
  AND token = '46XTNX5QAgzMMWlmyl49qBkFRUIj7L1Lqw4HWOqAczw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}