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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8efb98a48eb263cb67f5ccc094d986e10efb5e1edd5fb55555be5a81306f9f02' 
  AND token = 'pTP2NNooZM3XH5JL3cA9Q4WGjZIloBW+FHZ/JdECgw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}