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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ddcc8580ba5891a76ac42bda2df6958417d891fe8c6c8201f486f4e1c483d2b' 
  AND token = '4uBvkdp4Tey8y4g61iBK++SAQwlwFGhLb7EZLmXpJhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}