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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6001fab037beff05e28281cf6c4d26e1774ba2283244ff77b2e44280f68f0be3' 
  AND token = 'n72qhYipS5KuYy/QxzDYk/a+esej1AAIogZHB+HLLjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}